Holiday rentals in Mesopotamia
Find and book unique accommodation on Airbnb
Top-rated holiday rentals in Mesopotamia
Guests agree: these stays are highly rated for location, cleanliness and more.
Cabin in El Peñol
4.86 out of 5 average rating, 161 reviewsVilla Del Mar Jacuzzi Fireplace Pool & Boat Dock
The Breathtaking rock & lake views from our terraces, perfect size POOL & JACUZZI make our comfy cottage one of the most visited places in El Peñol & Guatape Amazing end of the tip peninsula landscape all surrounded by water & an ample boat dock Located in one of the best areas, our totally private cottage in the middle of nature, has all the amenities to assure the most espectacular experiences: KAYAK & PADDLE BOARDS, Pool Floats, hammocks, FIREPLACE, Charcoal/Propane BBQ grills, decks,viewers
Flat in Marinilla
5 out of 5 average rating, 7 reviewsSpacious 3BR Apt Near Airport | Gym, Sauna, Wi-Fi
Escape to your beautiful 3-bedroom apartment Oasis with breathtaking mountain views and easy access to Oriente. This hidden gem is 20 minutes from the airport, 43 minutes from Medellín and less than an hour from the world famous rock in Guatape. Perfect for small groups of 2-5 friends or family, our apartment is walkable to grocery stores and 5 minutes by car from a friendly neighborhood town. Perfect for monthly stays, inquire for discounted monthly rates. We look forward to hosting you!
Cabin in Guatapé
4.82 out of 5 average rating, 189 reviewsCottage "Jardin & Paisaje" in Guatapé amazing view
My place is good for couples, solo adventurers, families (with kids), big groups, and furry friends (pets). Hermosa casa de campo con vista y acceso a la represa. Totalmente amoblada. Area: 8000mt2, 200mt2 construidos. Todos los servicios públicos, Direct TV, juegos de mesa(parques, domino y cartas), elementos de pesca, piscina inflable para niños, zona de asados, áreas de descanso, chimenea, arboles frutales, areas ornamentales, legumbres, hortalizas, animales de granja y parqueadero.
Flat in El Poblado
4.93 out of 5 average rating, 201 reviewsNear Provenza, ModernStudio,A/C,Balcony,300MB WIFI
Welcome home, this perfect studio for a couple or solo traveler is the best option, you will have a balcony to enjoy the view of the north of Medellin, also a space to work with 300 Mbps Wifi, Kitchen equipment with all you need to cook, washer and dryer. Also A/C for those warm days. You will be able to walk to restaurants and grocery stores and a quick drive to Provenza and Park Lleras if you want to have fun. 24/7 Security Pool and Gym in the building *Please see our house rules
Island in Guatapé
4.99 out of 5 average rating, 72 reviewsStunning lakefront retreat, breathtaking views
Acua Lake House, experience the perfect blend of nature and luxury and in our special designed lake house with the best and unique view of la Piedra del Peñol. Every detail has been carefully curated to create a space that exudes comfort, relax, and a connection with the stunning surroundings. Prepare to be captivated by the awe-inspiring lake views, la Piedra del Peñol and its surrounding forest, that will greet you from the moment you step inside. Let us surprise you @acuaexperience
Flat in El Poblado
5 out of 5 average rating, 30 reviewsParadise 5G: Walking Distance from Provenza
Rainforest oasis on the river. Central location! Only 2 minutes walking from the best upscale restaurants in Provenza. Near the action, but you can't hear the noise. Luxury digital nomad paradise with everything you need to work in zen. Centrally located…yet feels like you're in a nature retreat. Quiet location, perfect for working remotely. Unique, eco-friendly design. Urban minimalist design meets Tulum-style tropical rainforest. Private jacuzzi on an open terrace with outdoor BBQ.
Apartment in El Poblado
4.89 out of 5 average rating, 97 reviewsBreathtaking views. El Poblado! Total Remodel!
Experience stylish luxury at this prime location. Enjoy all amenities, a peaceful ambience, and easy access to great restaurants, nightlife, and city attractions. The apartment is fully equipped with kitchen essentials and features a grand 75" living room TV. A secure, user-friendly safe is provided. Fluent in English, Spanish, and Polish, I'm here to assist you throughout your stay. Contact me with any concerns. Prepare for an unforgettable experience of elegance and convenience.
Flat in Envigado
5 out of 5 average rating, 8 reviews9802 Studio Apartment with Spectacular City View
Spacious and comfortable studio apartment where you can enjoy a spectacular panoramic view of the city’s south side, offering a pleasant and comfortable experience. This cozy space is perfect for your stay in Medellín, equipped with everything you need to feel right at home while you’re away. It’s ideally located in a safe and highly sought-after area, close to popular spots like bars, restaurants, salons, entertainment venues, nature, and more—all just a short distance away.”
Cabin in La Ceja
4.81 out of 5 average rating, 37 reviewsCasi Cielo! Heaven's Edge
Nestled 7,000 feet high, our tranquil cabin promises breathtaking mountain and waterfall vistas. This retreat, perfect for romantic getaways or family escapades, enchants with its warming fire pit and rejuvenating hot tub. Experience the stunning wilderness, bask in the magnificent scenery, and craft unforgettable memories. This is not just a stay, but an experience enveloped in serene beauty, embracing the extraordinary amidst the ordinary. (500 characters)
Apartment in El Poblado
4.9 out of 5 average rating, 152 reviewsTop Vacation & Business Apartment in Medellin
Modern apartment located in the best, most convenient and safest sector of Medellin. Featuring spectacular city views, this cozy and fully equipped high rise flat is perfect for a comfortable vacation or business trip. It is situated in a quiet residential neighborhood just a short 5 minute Uber or 15 minute walk to the city´s most visited entertainment district: the best restaurants, rooftop bars, cafes, nightclubs, boutiques, and more.
Flat in El Poblado
4.71 out of 5 average rating, 104 reviewsHighend 2 Bedroom Apt, Epic Manila, Private Garden
Welcome to our cozy 2-bedroom apartment, located in the vibrant neighborhood of Manila. This trendy area in el Poblado (best and safest area in Medellin), is surrounded by a wide variety of restaurants and cafes, offering everything a traveler needs for a perfect stay. You will find everything within walking distance: *Mininarkets, supermarkets *Gyms *Bars * Provenza *Parque el poblado * Parque lleras *Metro station
Flat in El Poblado
4.97 out of 5 average rating, 350 reviews*Top-Notch Penthouse | Poblado Near Parque Lleras*
Spectacular Penthouse with breathtaking 360 degree views of Medellin. Tastefully decorated and stocked with everything you need for an optimal stay. Strategically located within walking distance to all the boutiques, bars, coffee shops, malls, supermarkets, restaurants and nightlife in the Lleras / Provenza / Manila / Astorga neighborhoods of El Poblado.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for Mesopotamia holiday rentals
Other great holiday rentals in Mesopotamia
Cabin in Rionegro
4.94 out of 5 average rating, 186 reviewsNature & View
Flat in Belén
5 out of 5 average rating, 9 reviews#Stunning Panoramic Poblado- Medellín Skyline View
Cabin in Peñol
5 out of 5 average rating, 20 reviewsBabakan
Flat in Sabaneta
4.95 out of 5 average rating, 22 reviewsGreat View Private Apt Jacuzzi,Sauna, AC & W/D
Guest house in Rionegro
5 out of 5 average rating, 21 reviewsSpectacular estate near the airport and highway
Flat in Sabaneta
4.88 out of 5 average rating, 119 reviewsIntimate Loft with Private balcony - Class 48 2302
Flat in Itagüi
4.88 out of 5 average rating, 16 reviewsEnjoy local experience in the south
Home in El Poblado
5 out of 5 average rating, 7 reviewsElegant 10 rooms villa
Destinations to explore
- Pereira Holiday rentals
- Guatapé Holiday rentals
- Envigado Holiday rentals
- Sabaneta Holiday rentals
- Ibagué Holiday rentals
- La Vega Holiday rentals
- Cali Holiday rentals
- Bogotá Holiday rentals
- Medellin Metropolitan Area Holiday rentals
- Medellín Holiday rentals
- Medellín River Holiday rentals
- Eastern Antioquia Holiday rentals
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom