House holiday rentals in Panama

Find and book unique houses on Airbnb

Top-rated house rentals in Panama

Guests agree: these houses are highly rated for location, cleanliness and more.

0 of 0 items showing

1 of 3 pages

Guest favourite

Home in Río Hato

4.9 out of 5 average rating, 10 reviews

Adventure BigHouse - Beach House

Vive una experiencia única en ADVENTURE BIGHouse, ubicada en Ibiza Beach Residences I, Río Hato, Coclé – Panamá, con 4 hermosas piscinas y otras amenidades, y a 10 minutos de paradisiacas playas Santa Clara y La Pacora de arena blanca. INCLUYE: 4 habitaciones c/ baños privados Living y 1 sofá cama doble Comedor Cocina equipada Jardín privado Gacebo con parrillero y bar Entrada 2 pm Salida 1 pm del día siguiente Extensión sujeto a disponibilidad: Entrada 8 am y salida 5 pm Pet friendly

Superhost

Home in Bastimentos

4.81 out of 5 average rating, 108 reviews

Spacious, Over the Water Home with Plunge Pool

Perched over the water in Bastimentos Bay, this well-appointed four bedroom and three bath single family home combines classic Caribbean architecture with modern sensabilities. With over 2,000 sq ft of comfortably furnished spaces, there’s room enough for eight adults to spend time together - or apart - in any weather. BBQ poolside, stargaze from the hammocks, fish off the dock, walk to restaurants, or flag down a water taxi from your private boat dock for the ten minute trip to Bocastown.

Guest favourite

Home in Los Algarrobos

4.97 out of 5 average rating, 34 reviews

Spacious and bright new house by the creek (32)

New house 2022 by the river just outside David in Los Algarrobos. Close to the airport, Boquete, Volcan and it is only a few Kms away from Federal Mall in David. This house has all new appliances and furniture, over 600 mbps internet, over 200 channels, and HBO. The house has a huge kitchen, washer and dryer, two washrooms with showers and hot water. The water is filtered throughout the house. The backyard of the house is a river. There is a neighborhood security guard from 6pm to 6 am.

Guest favourite

Home in Los Algarrobos

4.99 out of 5 average rating, 136 reviews

New house! 5 min from David on the Boquete highway

It’s a new house (Oct 2019) just outside David in Los Algarrobos. Close to the airport, Boquete, Volcan and only 3.5km from the huge new Federal Mall in David. Evening security guards in the subdivision all year. Mountain views, covered parking, seconds from the boquete highway. This immaculate house has all new appliances and furniture, 5G internet, cable tv and Netflix. Your bilingual hosts live next door, the co-host (Grethel) is Panamanian, a lawyer and knows everything about Panama.

Guest favourite

Home in San Carlos

4.94 out of 5 average rating, 101 reviews

OceanView-Rooftop Jacuzzi&Pool | Concierge Service

Unique 3-story beach house – one of a kind. 7 bedrooms, 13 beds, 7.5 baths. hot water. Every room with full bath -AC’s and ceiling fans in all rooms, separate laundry -Rooftop area pool, Jacuzzi, bar, BBQ(charcoal & gas) with amazing ocean view -High ceilings, large open kitchen and living area. -Spacious balcony for dining or relaxing. - 5 min. walk to the beach. -Parking for up to 7 cars - Base price covers 4 guests (additional charge $40 per person). Sleeps up to 25 guests.

Guest favourite

Home in El Higo

4.93 out of 5 average rating, 45 reviews

Spacious beach house with pool in lush Paradise

Your home in Paradise. Unwind in Paradise at this unique, family-friendly beach house. Enjoy seclusion and security with your family and friends. Listen to the tropical birds, enjoy the mid-day breeze; appreciate the flowers and fruit trees of the lush garden from the hammocks; soak in the beautiful new pool; listen to soft music, barbecue, have a few drinks at the bohio's rustic bar, and have fun. 8-minute drive to the closest beach, 15-min to popular beaches in Santa Clara area.

Guest favourite

Home in Bocas del Toro District

4.92 out of 5 average rating, 212 reviews

Orange House - Over The Water Rentals

Enjoy golden sunsets across the bay from the Orange House at Over The Water Rentals. Home away from home in a tropical paradise. Relax on your outdoor lounge or explore the bay. The house has snorkel gear, SUP's & kayaks for guests to use for free. Located close to town & airport in a quiet local neighborhood. The house features a king size master bedroom & queen guest room, spacious hot water shower, handmade organic toiletries, fully equipped kitchen & high speed wifi

Superhost

Home in Vista Mar Golf, Beach & Marina

4.88 out of 5 average rating, 237 reviews

Luxurious Beach House - Private Pool Golf & Marina

Vista Mar Golf, Beach & Marina is a gated community with private security, with direct access to a state of the art golf course designed by J. Michael Poellot. It also has marina, heliport, tennis courts, direct private beach access, bars and restaurants. The house comes with an outdoor private pool & hot tub, also a amazing private outdoor kitchen, and an amazing sea view with spectacular sunrises and sunsets. any inquiry please contact 66168596

Guest favourite

Home in El Valle de Antón

4.94 out of 5 average rating, 136 reviews

Rustic family mountain home - 5 min walk to town!

Rustic family home with exquisitely landscaped garden complete with bridge over natural stream. Outdoor chill out space with barbecue and terrace under roof with hammocks on one side of the house, and a pergola with lounge area and gas grill on opposite side of the house. Centrally located to main attractions, only a 7 minute walk to the main market. Peaceful, relaxing refuge surrounded by views of nature and the cloud forest.

Guest favourite

Home in Contadora Island

4.95 out of 5 average rating, 21 reviews

Cozy Casa Ken

Looking for your home away from home in paradise? You have found it! Casa Ken sits across from the Priority Villas on the beautiful island of Contadora in the Gulf of Panama! Spoiler alert: Did you know the island gained more attention because of "Survivor - Exile Island"? This spacious house has room for your large family. Or if you're just looking for a place for a romantic get-away, we got you covered!

Superhost

Home in Cocle

4.96 out of 5 average rating, 99 reviews

Panama del Mar

Panama del Mar, nestled in center of Buenaventura, is truly a tropical paradise with a variety of pools, cabanas, pristine beach, restaurants, spas, and everything that makes your vacation relaxing. This spacious home accommodates 12 guests and includes all the conveniences of home. Any further questions can directed to Sandra to 507-6980-1314.

Superhost

Home in Bocas del Toro Province

4.87 out of 5 average rating, 117 reviews

Casa Clearwater... Your Caribbean Dream

Located in the tropical archipelago of Bocas Del Toro, Casa Clearwater calmly sits in the serene, crystal clear, blue waters of the Caribbean Sea. Built in 2014, the 4500 sq. foot tropical/modern design lies over a pristine reef on a private 9 acre property.......a unique & special place to spend a relaxing holiday.